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Updated: Sep 28, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Bioactive terpenoids from sunflower leaves cv. Peredovick
Francisco A Macías1, Ascensión Torres, José L G Galindo
1Grupo de Alelopati;a, Departamento de Qui;mica Orgánica, Facultad de Ciencias, Universidad de Cádiz, C/. República Saharaui s/n, Apdo. 40, 11510-Puerto Real, Spain. famacias@uca.es
Abstract:
The CH(2)Cl(2) extract of dried leaves of Helianthus annuus L. cv. Peredovick(R) has yielded, in addition to the known sesquiterpene lactones annuolide E and leptocarpin, and the sesquiterpenes heliannuols A, C, D, F, G, H, I, the new bisnorsesquiterpene, annuionone E, and the new sesquiterpenes heliannuol L, helibisabonol A and helibisabonol B. Structural elucidation was based on extensive spectral (one and two-dimensional NMR experiments) and theoretical studies. The sesquiterpenes heliannuol A and helibisabonol A and the sesquiterpene lactone leptocarpin inhibited the growth of etiolated wheat coleoptiles.
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