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Related Experiment Videos

Evolution of descending optic atrophy. A case report.

M Lundström, L Frisén

    Acta Ophthalmologica
    |November 1, 1975
    PubMed
    Summary

    Severe intracranial optic nerve trauma causes blindness and gradual fundus changes. Retinal nerve fiber layer loss and optic disc pallor occur over 12 weeks.

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    Area of Science:

    • Ophthalmology
    • Neuroscience
    • Trauma research

    Background:

    • Severe head trauma can impact the optic nerve, leading to vision loss.
    • Understanding the timeline of ocular changes post-optic nerve injury is crucial for prognosis.

    Observation:

    • Serial fundus photography documented changes in a blind eye following intracranial optic nerve trauma.
    • Initial observation showed minimal changes in the first 4 weeks post-trauma.

    Findings:

    • Gradual disappearance of the retinal nerve fiber layer occurred between weeks 4 and 8.
    • Retinal vessels narrowed, and vascular pseudo-sheathing near the optic disc was noted.
    • Optic disc pallor peaked at 12 weeks, with a mottled peripapillary retina.

    Implications:

    • Establishes a temporal sequence of fundus alterations after intracranial optic nerve injury.
    • Provides a reference for monitoring and understanding visual field defects and optic neuropathy progression.
    • Highlights the delayed onset of maximal optic disc pallor and associated retinal changes.

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