Study on embryo morphology and clinical result of intracytoplasmic sperm injection for infertility
Min-Zhen Huang1, Shi-Ling Chen, Fu-Qi Xing
1Center for Assisted Reproduction, Department of Obstetrics and Gynecology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.
Abstract:
OBJECTIVE: To explore the relevance of the embryo morphology with the clinical result of intracytoplasmic sperm injection (ISCI) for infertility treatment. METHODS: A retrospective analysis was conducted of 291 ISCI and 352 in vitro fertility (IVF) cycles collected during the period from Juanary, 1999 to March, 2001. RESULTS: Significant difference was not found in the fertility rates between the 2 groups (75.7% vs 73.2%, P=0.5738), nor in the oocyte lysis rates (10.6% vs 7.9%, P=0.238). The rates of the embryos with more than 20% fragments were similar between the 2 groups (41.2% vs 55.8%, P=0.137), but ICSI group had a significantly lower rate of blastocyst formation (43.1% vs 55.8%, P<0.001). The clinical pregnancy rates and miscarriage rates did not vary significantly between the 2 groups (34.7% vs 39.9%, P=0.189; 8.9% vs 13.4%, P=0.079). CONCLUSIONS: ISCI is an effective treatment for male infertility to achieve uneventful clinical pregnancy.
