Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Topical hyperbaric oxygen and electrical stimulation: exploring potential synergy.

Laura E Edsberg1, Michael S Brogan, C David Jaynes

  • 1Natural and Health Sciences Research Center, Daemen College, 4380 Main Street, Amherst, NY 14226, USA. Leedsberg@aol.com

Ostomy/Wound Management
|November 12, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Using Explainable Artificial Intelligence in a Systematic Literature Review of Pressure Injury Prevention: Lessons Learned.

Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society·2026
Same author

Introduction to Artificial Intelligence for the Wound, Ostomy, and Continence Nurse.

Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society·2025
Same author

Utilization of Pressure Injury Prevention Interventions in Acute Care Hospitals.

The American journal of nursing·2025
Same author

Incontinence Management and Pressure Injury Rates in US Acute Care Hospitals: Analysis of Data From the 2018-2019 International Pressure Injury Prevalence™ (IPUP) Survey.

Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society·2022
Same author

Implementation of Pressure Injury Prevention Strategies in Acute Care: Results From the 2018-2019 International Pressure Injury Prevalence Survey.

Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society·2022
Same author

Pressure Injuries in Critical Care Patients in US Hospitals: Results of the International Pressure Ulcer Prevalence Survey.

Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society·2022

Topical hyperbaric oxygen therapy significantly aids chronic wound healing, particularly pressure ulcers. Combining it with electrical stimulation showed no added benefit in this preliminary study.

Area of Science:

  • Wound Healing
  • Hyperbaric Medicine
  • Geriatric Care

Background:

  • Chronic wounds, especially pressure ulcers in geriatric patients, present a significant clinical challenge.
  • Traditional treatments often have limitations, driving the need for innovative therapeutic modalities.
  • Topical hyperbaric oxygen (THBO) and electrical stimulation (ES) are emerging as promising interventions.

Purpose of the Study:

  • To evaluate the preliminary efficacy of topical hyperbaric oxygen therapy (THBO) in healing chronic wounds.
  • To assess the combined effect of THBO and electrical stimulation (ES) on wound healing.
  • To gather initial data on healing times and wound size reduction.

Main Methods:

  • A prospective, uncontrolled study involving geriatric residents with Stage III or IV pressure ulcers.

Related Experiment Videos

  • Eight subjects received daily THBO; three of these also underwent ES.
  • Wound size and healing progress were monitored over 8 to 49 weeks.

    • Main Results:

    • After 4 weeks, THBO treatment resulted in an average wound size decrease of 34.4%.
    • Five subjects experienced over 20% wound size reduction, averaging 51.8% reduction.
    • No significant difference in healing outcomes was found between THBO alone and THBO with ES.

    Conclusions:

    • Preliminary findings suggest THBO effectively facilitates healing and closure of pressure ulcers.
    • THBO appears beneficial for both diabetic and non-diabetic patients with chronic wounds.
    • Further investigation via a multicenter, randomized controlled trial is warranted.