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Conserved expression pattern of BMP-2/4 in hemichordate acorn worm and echinoderm sea cucumber embryos

Yoshito Harada1, Eiichi Shoguchi, Shunsuke Taguchi

  • 1Department of Zoology, Graduate School of Science, Kyoto University, Japan.

Zoological Science
|November 12, 2002
PubMed

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Determination01:51

Determination

During embryogenesis, cells become progressively committed to different fates through a two-step process: specification followed by determination. Specification is demonstrated by removing a segment of an early embryo, “neutrally” culturing the tissue in vitro—for example, in a petri dish with simple medium—and then observing the derivatives. If the cultured region gives rise to cell types that it would normally generate in the embryo, this means that it is specified. In contrast, determination...