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Sequence of goat cyclin T1 cDNA, gene organisation and expression analysis
Xavier Mata1, Sead Taourit, Jean Luc Vilotte
1Laboratoire de Génétique Biochimique et de Cytogénétique, INRA, Jouy-en-Josas, France. mata@diamant.jouy.inra.fr
Biochimica Et Biophysica Acta
|November 13, 2002
Abstract:
The cyclin T1 (Cyc T1) protein has been recently identified, associated with the cyclin-dependent kinase 9 (CDK 9), as to be involved in the transcriptional activation of the Human Immunodeficiency Virus type 1 (HIV-1) by the Tat protein. In this study, the sequence of the 7 kb goat Cyc T1 cDNA is reported as well as the exon/intron structure of the gene. Its observed ubiquitous expression is consistent with the promoter structure.