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Effect on mood of subthalamic DBS for Parkinson's disease: a consecutive series of 24 patients

A Berney1, F Vingerhoets, A Perrin

  • 1Department of Psychiatry, CHUV, Lausanne, Switzerland. aberne1@po-box.mcgill.ca

Neurology
|November 13, 2002
PubMed

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Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of its...