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[False aneurysm due to mycotic angitis-case report (author's transl)]
No Shinkei Geka. Neurological Surgery
|June 1, 1975
Summary
A rare case of Aspergillus-induced angitis led to a false aneurysm in the internal carotid artery, ultimately causing fatal meningitis. This highlights a severe complication of fungal infections in cerebral vasculature.
Area of Science:
- Neurology
- Infectious Diseases
- Vascular Surgery
Background:
- Cerebral mycotic angitis is a secondary inflammation of arteries, often affecting the vasa vasorum and associated with cardiac disease.
- It commonly involves the middle cerebral artery but rarely occurs with primary brain or dura mater infections.
Observation:
- A 26-year-old male presented with neurological deficits after surgery for an arteriovenous malformation.
- He developed meningitis and subsequently a false aneurysm in the internal carotid artery despite antibiotic therapy.
Findings:
- Histological examination revealed Aspergillus-induced angitis as the cause of the internal carotid artery perforation.
- The patient succumbed to aggravated meningitis following surgical repair attempts.
Implications:
- This case underscores the potential for invasive fungal infections, like Aspergillus, to cause devastating vascular complications in the brain.
- It highlights the critical need for prompt diagnosis and aggressive management of fungal angitis, particularly in immunocompromised or post-surgical patients.
- Further research into the pathogenesis and treatment of fungal cerebral angitis is warranted.