Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Induced hypotension for endoscopic sinus surgery].

Kazuhiko Saitoh1, Hideo Suzuki, Akiko Hiruta

  • 1Department of Anesthesiology and Intensive Care Medicine, Jichi Medical School, Tochigi 329-0498.

Masui. the Japanese Journal of Anesthesiology
|November 14, 2002
PubMed
Summary

Controlled hypotension using sodium nitroprusside significantly improved surgical field dryness and reduced blood loss during endoscopic sinus surgery (ESS). This technique enhances surgical conditions for patients undergoing ESS.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pretreatment Tumor-infiltrating CD8<sup>+</sup> T Cell Numbers Are Associated With the Response to Tremelimumab Plus Durvalumab in Hepatocellular Carcinoma.

Anticancer research·2026
Same author

Neural basis of successful DBS for OCD after failed capsulotomy.

medRxiv : the preprint server for health sciences·2026
Same author

Prefrontal cortex connectivity profiles distinguish rapid from slow responders to deep brain stimulation in obsessive-compulsive disorder.

medRxiv : the preprint server for health sciences·2026
Same author

White Matter Integrity Correlates with Strength of Response to Deep Brain Stimulation in Treatment-Resistant Obsessive-Compulsive Disorder.

medRxiv : the preprint server for health sciences·2026
Same author

Conserved fiber topography of the anterior limb of the internal capsule in treatment-resistant psychiatric patients.

bioRxiv : the preprint server for biology·2026
Same author

Response-survival Association Differs by Hepatic Reserve in Unresectable HCC Receiving Atezolizumab Plus Bevacizumab.

Cancer diagnosis & prognosis·2026

Area of Science:

  • Otolaryngology
  • Anesthesiology
  • Surgical Innovation

Background:

  • Endoscopic sinus surgery (ESS) requires optimal surgical field visualization.
  • Achieving a dry surgical field can be challenging in ESS.
  • Minimizing blood loss is crucial for patient safety and surgical efficiency.

Purpose of the Study:

  • To evaluate the efficacy of induced hypotension in improving surgical field dryness during ESS.
  • To compare blood loss and surgical conditions between controlled hypotension and normotension groups.

Main Methods:

  • A randomized controlled trial involving 2 groups of adult patients (ASA physical status I and II) undergoing ESS.
  • Group C: Mean arterial blood pressure (MAP) maintained around 80 mmHg.
  • Group H: Sodium nitroprusside infusion to maintain MAP around 60 mmHg (induced hypotension).

Related Experiment Videos

Main Results:

  • Significantly improved surgical field dryness in the induced hypotension group (Group H).
  • Significantly decreased blood loss in the induced hypotension group (Group H).
  • No significant differences in fluid infusion volume, urine output, or surgical/anesthetic times between groups.

Conclusions:

  • Induced hypotension with sodium nitroprusside is an effective method to enhance surgical conditions in ESS.
  • This technique leads to a drier surgical field and reduced blood loss, benefiting surgical outcomes.