[Two years experience with the new accommodative 1 CU intraocular lens]

Area of Science:

• Ophthalmology
• Biomedical Engineering
• Optics

Background:

• Cataract surgery has advanced significantly, but presbyopia remains a challenge.
• Accommodative intraocular lenses (IOLs) aim to restore the eye's natural focusing ability.
• The 1CU lens utilizes an 'optic-shift' concept to mimic natural accommodation.

Purpose of the Study:

• To evaluate the safety and efficacy of the 1CU accommodative IOL.
• To assess the accommodative performance and visual outcomes in patients implanted with the 1CU IOL.
• To validate the 'optic-shift' mechanism of the 1CU lens.

Main Methods:

• Over 90 patients received the 1CU IOL, with outcomes compared to conventional IOL control groups.
• Clinical studies assessed implantability, centration, visual acuity, and accommodative range.
• Axial lens movement was measured after medical stimulation and inhibition of the ciliary muscle.

Main Results:

• The 1CU IOL demonstrated safe and effective implantation with good centration and no IOL-specific complications.
• Patients with the 1CU IOL achieved significantly better distance-corrected near visual acuity and a larger accommodative range.
• The lens optic showed expected anterior and posterior movement, confirming the 'optic-shift' concept.

Conclusions:

• The 1CU accommodative IOL is a safe and effective option for presbyopia correction.
• The 'optic-shift' concept is validated, showing potential for restoring natural focusing.
• Further multicenter studies are needed to confirm long-term outcomes and accommodative results.