Synthesis and pharmacological properties of some 1-aryl-4(1H)-pyrido(2,3-d)pyrimidones

Some 1-aryl-4(1H)-pyrido[2,3-d]pyrimidones were synthesized from the corresponding 2-anilinonicotinamides by cyclization with triethyl-orthoformate. This series of compounds is a new one with interesting antiinflammatory and hypno-sedative properties.