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Visualizing the structure and mechanism of a small nucleolytic ribozyme

William G Scott1

  • 1Department of Chemistry and Biochemistry, Center for Molecular Biology of RNA, University of California, Santa Cruz, CA 95064, USA. wgscott@chemistry.ucsc.edu

Methods (San Diego, Calif.)
|November 15, 2002
PubMed
Summary

Time-resolved crystallography now reveals enzyme intermediates at atomic resolution. This study applies X-ray crystallography freeze-trapping to the hammerhead ribozyme, an RNA enzyme, to observe its dynamic states.

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