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A case of hypersensitivity syndrome due to phenytoin
Yayoi Nagai1, Tomoyasu Hattori, Osamu Ishikawa
1Department of Dermatology, Tone Central Hospital, Numata, Gunma, Japan.
The Journal of Dermatology
|November 16, 2002
Abstract:
We report a 30-year-old female with hypersensitivity syndrome (HS) due to phenytoin. Her disease course was typical with elevation of the antibody titer for human herpes virus 6. Three courses of methylpredonisolone pulse therapy were required to control the disease activity. Since the pathogenic mechanism and treatments for HS have not been established, further clinical analyses are warranted.