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[Therapeutic effect of puerarin therapy on sudden deafness]
Jian-Min Liu1, Li Ma, Wei-Ping He
1Department of Otorhinolaryngology, Shenzhen Hospital of Guangdong General Command of Border Defense of Armed Police, China 518029.
Objective:
To evaluate the therapeutic effect of puerarin in the treatment against sudden deafness.
Methods:
Seventy-two patients with sudden deafness were randomly assigned into therapeutic group (n= 40) who received intravenous infusion of puerarin injection and the control group (n=32) who were given intravenous infusion of anisodamine. The therapeutic effects of the two treatments were observed and compared.
Results:
The total efficacy rates against sudden deafness and tinnitus in the therapeutic group were 89.68 % and 84.37 % respectively, but only 62.5 % and 56.52 % respectively in the control group, showing significant difference (P<0.05).
Conclusion:
Puerarin is effective in dilating the blood vessels and promoting microcirculation of the inner ear, with significant therapeutic effect in the treatment of sudden deafness.