Do intraoperative variables have an effect on the timing of tracheal extubation after coronary artery bypass graft surgery?
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Updated: Sep 28, 2026

Non-Intubated Video-Assisted Thoracoscopic Surgery
Published on: May 26, 2023
1School of Health Care/School of Biological and Molecular Sciences, Oxford Brookes University, Oxford, United Kingdom. hewalthall@brookes.ac.uk
Insights
This study found no intraoperative variables significantly impacted extubation time after coronary artery bypass graft surgery. Early extubation is achievable, though further research into cardiac status and ischemia is suggested.
Area of Science:
- Cardiothoracic Surgery
- Anesthesiology
- Intensive Care Medicine
Background:
- Coronary artery bypass graft (CABG) surgery is a common procedure.
- Optimizing postoperative recovery, including extubation time, is crucial for patient outcomes.
- Identifying factors influencing extubation can improve resource allocation and patient management.
Purpose of the Study:
- To determine if intraoperative variables significantly affect extubation time following CABG surgery.
- To investigate the relationship between specific surgical parameters and the duration of mechanical ventilation.
Main Methods:
- Retrospective analysis of 89 patients undergoing CABG surgery.
- Data collected included intraoperative variables: number of vessels grafted, cardiopulmonary bypass (CPB) time, operation length, and internal mammary artery use.
- Extubation time was the primary outcome measure.
Main Results:
- The mean extubation time was 4.97 hours.
- Linear regression analysis revealed no statistically significant intraoperative variables influencing extubation time (P = .05).
- Low mean CPB time (49.1 minutes) may have influenced the observed lack of significant association.
Conclusions:
- Early extubation after CABG surgery can be safely achieved.
- No single intraoperative variable was identified as a significant predictor of extubation time in this cohort.
- Further investigation is warranted regarding the interplay of cardiac status, ischemia, and extubation timing.
Objective:
The purpose of this study was to investigate whether any intraoperative variable had a significant effect on extubation time after coronary artery bypass graft surgery.
Design:
Study design was a retrospective study.
Setting:
Study took place in 1 cardiac center in the United Kingdom that had 1000 cases per year.
Subjects:
Eighty-nine patients had coronary artery bypass graft surgery in the first 6 months of 1998 performed by one consultant cardiac surgeon.
Outcome Measures:
Study measures included intraoperative variables (number of vessels grafted, time on cardiopulmonary bypass [CPB], length of the operation, use of internal mammary artery) and extubation time.
Results:
Mean extubation time was 4.97 hours. On analysis via linear regression no intraoperative variables were found to be statistically significant (P = .05) to extubation time.
Conclusion:
This study identified that early extubation can be achieved safely. Although no variable was found to have a significant effect on extubation time, the relationship between CPB and extubation may have been attributed to the low mean CPB time within the study (49.1 minutes). The relationship between cardiac status, ischemia, and the timing of extubation does warrant additional exploration.
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