Endoscopic sinus surgery in cases of cholesterol granuloma of the maxillary sinus
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Updated: Sep 28, 2026

Endoscopic Cholesteatoma Surgery
Published on: January 19, 2022
Toshihiko Kikuchi1, Eigo So, Kotaro Ishimaru
1Department of Otorhinolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan. toshi@orl.med.tohoku.ac.jp
Abstract:
Cholesterol granuloma is usually associated with middle ear disease and is very rare in the paranasal sinuses. We report a case of cholesterol granuloma originating in the maxillary sinus of a 52-year-old female. Endoscopic sinus surgery was performed on the left maxillary sinus, and the cholesterol granuloma was successfully removed by the middle meatal antrostomy. Light microscopic examination showed granulomatous tissue with typical cholesterol clefts, multinucleated foreign body giant cells, small areas of hemorrhage, hemosiderin-laden macrophages and plasma cells. We also describe the details of the endoscopic surgical techniques employed in the treatment of this disorder.
