Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Colchicine for periodic peritonitis.

H A Reimann

    JAMA
    |January 6, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Colchicine effectively suppressed periodic peritonitis, also known as familial Mediterranean fever, in most patients after decades of failed treatments. This finding highlights colchicine

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Infectious Diseases: Annual Review of Significant Publications.

    Postgraduate medical journal·2011
    Same author

    Cholera in Chungking in 1945; use of streptomycin.

    Journal of bacteriology·2010
    Same author

    Antibiotics.

    Bulletin. Chicago Medical Society·2010
    Same author

    Habitual hyperthermia; premenstrual fever.

    Journal of the American Medical Association·2010
    Same author

    Viral infections of respiratory tract; their treatment and prevention.

    Journal of the American Medical Association·2010
    Same author

    Asiatic cholera; clinical study and experimental therapy with streptomycin.

    The American journal of tropical medicine and hygiene·2010
    Same journal

    WHO Issues Guidelines for Treating Ebola and Marburg Viruses.

    JAMA·2026
    Same journal

    FDA Approves Additional Naloxone Nasal Spray for Opioid Overdose.

    JAMA·2026
    Same journal

    HIV May Hide in More Cells Than Previously Thought-Here's What That Could Mean for a Cure.

    JAMA·2026
    Same journal

    US Dietary Supplement Use Increasing, Especially in Older Adults.

    JAMA·2026
    Same journal

    Heat Stress From Climate Change Surges Globally.

    JAMA·2026
    Same journal

    Strength Training Linked With Lower Cardiovascular Disease Risk in Women.

    JAMA·2026
    See all related articles

    Area of Science:

    • Internal Medicine
    • Rheumatology
    • Genetics

    Background:

    • Periodic peritonitis, including familial Mediterranean fever, has historically presented therapeutic challenges.
    • Previous treatment strategies over 25 years yielded limited success.

    Purpose of the Study:

    • To evaluate the efficacy of colchicine in managing periodic peritonitis.
    • To assess colchicine's role in patients with recurrent polyserositis.

    Main Methods:

    • A cohort of 14 patients with periodic peritonitis was treated with colchicine.
    • Continuous daily dosage of 0.65 mg was administered.
    • Intermittent therapy protocols are currently under investigation.

    Main Results:

    Related Experiment Videos

  • Colchicine suppressed episodes in 12 out of 14 patients.
  • The drug demonstrated significant efficacy where prior trials failed.

    • Conclusions:

    • Colchicine is a highly effective treatment for periodic peritonitis (familial Mediterranean fever).
    • Suppression of episodes by colchicine may serve as a diagnostic criterion.
    • Further research into intermittent dosing strategies is warranted.