Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Routine preoperative laboratory analyses are unnecessary before elective laparoscopic cholecystectomy.

T N Robinson1, W L Biffl, E E Moore

  • 1Department of Surgery, Denver Health Medical Center/University of Colorado Health Sciences Center, Denver, CO, USA.

Surgical Endoscopy
|November 19, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Haematobia irritans parasitism of F1 yak × beef cattle (Bos grunniens × Bos taurus) hybrids.

Medical and veterinary entomology·2019
Same author

Large volume polymerized haemoglobin solution in a Jehovah's Witness following abruptio placentae.

Transfusion medicine (Oxford, England)·2004
Same author

Neutrophil apoptosis is delayed by trauma patients' plasma via a mechanism involving proinflammatory phospholipids and protein kinase C.

Surgical infections·2003
Same author

Fibroblast growth factor-18 is a trophic factor for mature chondrocytes and their progenitors.

Osteoarthritis and cartilage·2002
Same author

Clinical applications of cardiovascular angiogenesis.

Journal of cardiac surgery·2002
Same author

The abdominal compartment syndrome is a morbid complication of postinjury damage control surgery.

American journal of surgery·2002
Same journal

Efficacy and safety of transoral incisionless fundoplication in non-obese and obese adults: a population-based cohort study from the United States.

Surgical endoscopy·2026
Same journal

Minimally invasive versus open surgery for adhesive small bowel obstruction: a systematic review and meta-analysis.

Surgical endoscopy·2026
Same journal

Enhanced view/extended totally extraperitoneal plasty (eTEP) Rives-Stoppa repair versus open Rives-Stoppa repair: a single-center retrospective propensity score-matched cohort study.

Surgical endoscopy·2026
Same journal

Robotic-assisted endoscopic submucosal dissection: a scoping review of preclinical and early clinical evidence.

Surgical endoscopy·2026
Same journal

Conversion of endoscopic sleeve gastroplasty to bariatric surgery.

Surgical endoscopy·2026
Same journal

Artificial intelligence and chatbots in general surgery: a survey among surgeons in Germany, Austria and Switzerland.

Surgical endoscopy·2026
See all related articles

Routine liver function tests (LFTs) before elective laparoscopic cholecystectomy (LC) are not cost-effective. History and physical (H&P) and ultrasound (US) are sufficient for preoperative evaluation, as LFTs provide no additional useful information.

Area of Science:

  • Gastroenterology
  • Surgical Innovation
  • Clinical Pathway Development

Background:

  • A clinical pathway (CP) for elective laparoscopic cholecystectomy (LC) was developed, incorporating history and physical (H&P), right upper quadrant ultrasound (US), and liver function tests (LFTs).
  • The hypothesis was that routine LFTs do not alter management beyond H&P and US findings and could be excluded from the CP.

Purpose of the Study:

  • To evaluate the necessity and cost-effectiveness of routine liver function tests (LFTs) in the preoperative assessment for elective laparoscopic cholecystectomy (LC).
  • To determine if LFTs provide additional diagnostic value beyond history and physical (H&P) and ultrasound (US) in identifying choledocholithiasis or other unexpected outcomes.

Main Methods:

  • A study of 387 consecutive patients undergoing elective LC was conducted.

Related Experiment Videos

  • Preoperative evaluation abnormalities from H&P, US, and LFTs were compared with intraoperative findings of choledocholithiasis or unexpected outcomes.
  • Main Results:

    • Abnormalities were detected in 48% of patients: H&P (n=7), US (n=13), and LFTs (n=177).
    • Only 2% of patients (n=7) had documented choledocholithiasis, with findings distributed across H&P (2), US (3), and LFTs (4).
    • No patient with choledocholithiasis presented with abnormal LFTs alongside normal H&P and US findings.

    Conclusions:

    • Routine liver function tests (LFTs) are not cost-effective for preoperative evaluation before elective laparoscopic cholecystectomy (LC).
    • History and physical (H&P) and ultrasound (US) are valuable components of the preoperative assessment for LC.
    • LFTs do not contribute significant additional information and should not be routinely included in the preoperative evaluation for elective LC.