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Related Experiment Videos

Distrust, race, and research.

Giselle Corbie-Smith1, Stephen B Thomas, Diane Marie M St George

  • 1Department of Social Medicine, The University of North Carolina at Chapel Hill, Campus Box 7240, Chapel Hill, NC 27599, USA. gcorbie@med.unc.edu

Archives of Internal Medicine
|November 20, 2002
PubMed
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African Americans exhibit higher distrust in medical research compared to white Americans, even after accounting for social class. This distrust impacts clinical trial recruitment and requires attention from researchers.

Area of Science:

  • Medical research ethics
  • Health disparities
  • Clinical trial recruitment

Background:

  • Distrust in research and the medical community is a known barrier to recruiting African Americans into clinical trials.
  • Investigator concerns highlight the need to understand racial differences in trust.

Purpose of the Study:

  • To investigate racial disparities in distrust towards medical research.
  • To assess the influence of sociodemographic factors on racial differences in distrust.

Main Methods:

  • Analysis of a national telephone survey data from 527 African American and 382 white respondents.
  • Utilized a 7-item index to measure distrust as the primary outcome.

Main Results:

  • African Americans reported lower trust in physicians explaining research participation and higher belief in unnecessary risks.
Keywords:
Biomedical and Behavioral ResearchEmpirical Approach

Related Experiment Videos

  • Mean distrust scores were significantly higher for African American respondents (3.1 vs 1.8).
  • Race remained a strong predictor of higher distrust (OR 4.7) even after controlling for sociodemographic variables.

    • Conclusions:

    • Significant racial differences in distrust persist, with African Americans showing less trust than white Americans, independent of social class.
    • These disparities in distrust have critical implications for engaging African Americans in clinical research.