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[Phospholipids under combined ozone-oxygen administration].

E Müller-Tyl, P Hernuss, H Salzer

    Osterreichische Zeitschrift Fur Onkologie. Austrian Journal of Oncology
    |January 1, 1975
    PubMed
    Summary
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    Parenteral oxygen-ozone therapy in women with gynecological cancer reduced key phospholipids like lecithin and sphingomyelin. These changes occurred within normal physiological ranges, suggesting a metabolic influence of ozone on fat processing.

    Area of Science:

    • Biochemistry
    • Oncology
    • Medical Ozone Therapy

    Context:

    • Parenteral oxygen-ozone gas mixture is used for various diseases.
    • Ozone is known to influence fat metabolism.
    • Phospholipids play crucial roles in cellular functions.

    Purpose:

    • To investigate the effect of oxygen-ozone gas mixture on phospholipid levels.
    • To analyze ozone's influence on fat metabolism, specifically in phospholipids.
    • To assess changes in lecithin, lysolecithin, cephalin, and sphingomyelin.

    Summary:

    • Forty women with gynecological cancer received 10 ml of oxygen-ozone gas mixture (450 gamma ozone) intravenously.
    • Venous blood samples were collected before and 10 minutes after treatment.
    • Levels of lecithin, lysolecithin, cephalin, and sphingomyelin were determined using Randerath's method.

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    Impact:

    • A decrease in all four measured phospholipids (lecithin, lysolecithin, cephalin, sphingomyelin) was observed.
    • Despite the decrease, all phospholipid levels remained within normal physiological ranges.
    • This suggests a potential metabolic effect of oxygen-ozone therapy on lipid profiles in cancer patients.