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Updated: Jul 28, 2026

Transuterine Fetal Tracheal Occlusion Model in Mice
Published on: February 5, 2021
Hypohidrotic ectodermal dysplasia associated with squamous cell carcinoma of the trachea
1Department of Otolaryngology, Radcliffe Infirmary, Oxford, UK.
Abstract:
Hypohidrotic ectodermal dysplasia (HED) is a rare condition characterized by abnormalities to ectodermal derived tissues although other organs or systems are frequently involved. Patients with HED can have a number of symptoms that may lead them to present to the otolaryngologist. We present a case of a 37-year-old female with HED who initially presented with nasal obstruction but then very rapidly developed stridor due to a tracheal squamous cell carcinoma. We suggest a possible association between HED and carcinoma of the upper respiratory tract that has not previously been reported.
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