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Anxiety sensitivity and panic disorder.

Richard J McNally1

  • 1Department of Psychology, Harvard University, Cambridge, Massachusetts 02138, USA.

Biological Psychiatry
|November 20, 2002
PubMed
Summary
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Anxiety sensitivity, a fear of anxiety sensations measured by the Anxiety Sensitivity Index (ASI), predicts panic symptoms and attacks. Treatments like cognitive behavioral therapy and imipramine can reduce anxiety sensitivity.

Area of Science:

  • Psychology
  • Clinical Psychology
  • Psychiatry

Background:

  • Anxiety sensitivity involves fearing anxiety-related sensations.
  • The Anxiety Sensitivity Index (ASI) is a common measure.
  • Elevated anxiety sensitivity is prevalent in panic disorder.

Purpose of the Study:

  • To examine the predictive validity of anxiety sensitivity for panic symptoms.
  • To investigate the role of anxiety sensitivity as a risk factor for panic.
  • To assess the impact of treatments on anxiety sensitivity.

Main Methods:

  • Utilized the Anxiety Sensitivity Index (ASI) for measurement.
  • Examined ASI scores in relation to biological challenges (e.g., CO2 inhalation).
  • Conducted prospective longitudinal studies to track panic attacks.

Related Experiment Videos

  • Assessed changes in ASI scores following cognitive behavioral treatment and imipramine.

    • Main Results:

    • ASI scores predict panic symptoms in response to challenges.
    • Elevated ASI scores predict future spontaneous panic attacks.
    • Cognitive behavioral treatment and imipramine decrease anxiety sensitivity.

    Conclusions:

    • Anxiety sensitivity is a significant risk factor for panic and panic disorder.
    • Reducing anxiety sensitivity may prevent panic relapse.
    • Pharmacological and psychological interventions can effectively lower anxiety sensitivity.