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Using ECG-gated multidetector CT to evaluate global left ventricular myocardial function in patients with coronary
Kai Uwe Juergens1, Matthias Grude, Eva Maria Fallenberg
1Department of Clinical Radiology, University of Muenster, Albert-Schweitzer-Str. 33, D-48149 Muenster, Germany.
Insights
Multidetector CT coronary angiography with retrospective ECG gating can assess left ventricular function. This method shows good correlation with biplane cineventriculography in patients with coronary artery disease.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Multidetector CT (MDCT) coronary angiography provides 3D volume data.
- Retrospective ECG gating allows reconstruction of cardiac phases (diastole and systole).
Purpose of the Study:
- To assess the feasibility of determining left ventricular (LV) function using MDCT coronary angiography data.
- To correlate MDCT-derived LV function with biplane cineventriculography in patients with coronary artery disease.
Main Methods:
- Retrospective analysis of ECG-gated 3D MDCT coronary angiography datasets.
- Image reconstruction of diastolic and systolic phases for LV contour delineation.
- Comparison of MDCT findings with biplane cineventriculography.
Main Results:
- MDCT allowed clear visualization of endocardial and epicardial LV borders.
- Functional data derived from MDCT showed acceptable correlation with biplane cineventriculography (r = 0.8; p < 0.05).
Conclusions:
- MDCT coronary angiography with retrospective ECG gating is feasible for assessing LV function.
- This technique provides reliable functional data comparable to biplane cineventriculography in patients with coronary artery disease.
Objective:
Retrospectively ECG-gated three-dimensional volume data from multidetector CT (MDCT) coronary angiography enable image reconstruction of the cardiac cycle in the diastolic and systolic phases. The objective of our study was to investigate the feasibility of determining left ventricular function from MDCT coronary angiography data sets in 22 patients with coronary artery disease and to study the correlation of MDCT results with those of functional data from biplane cineventriculography.
Conclusion:
Multiplanar reformations from three-dimensional MDCT data allowed good delineation of endocardial and epicardial left ventricular contours. In patients evaluated for coronary artery disease, MDCT coronary angiography with retrospective ECG gating provides functional data in an acceptable correlation (r = 0.8; p < 0.05) to biplane cineventriculography.