Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ions, channels, and receptors.

David A Powis1, Philip D Marley

  • 1School of Biomedical Sciences, University of Newcastle, Callaghan, NSW 2308, Australia. david.powis@newcastle.edu.au

Annals of the New York Academy of Sciences
|November 20, 2002
PubMed
Summary

This research explores chromaffin cell signaling mechanisms, focusing on neuronal nicotinic receptors, calcium signals, and cell surface transporters. These findings enhance our understanding of how these cells regulate their functional activity.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Is the UCAT appropriate for selecting undergraduate medical students?

The Medical journal of Australia·2021
Same author

Excitotoxic stimulation of brain microslices as an in vitro model of stroke.

Journal of visualized experiments : JoVE·2014
Same author

Selecting medical students.

The Medical journal of Australia·2008
Same author

Maturational changes in the subunit composition of AMPA receptors and the functional consequences of their activation in chicken forebrain.

Developmental neuroscience·2006
Same author

Selecting medical students: evidence based admissions procedures for medical students are being tested.

BMJ (Clinical research ed.)·2006
Same author

Segmental differences in the roles of rho-kinase and protein kinase C in mediating vasoconstriction.

The Journal of pharmacology and experimental therapeutics·2006

Area of Science:

  • Cell Biology
  • Neuroscience
  • Biochemistry

Background:

  • Chromaffin cells are crucial for regulating physiological responses.
  • Understanding their signaling is key to various biological processes.

Purpose of the Study:

  • To investigate the properties of neuronal nicotinic receptors in chromaffin cells.
  • To elucidate the mechanisms shaping calcium signals in these cells.
  • To examine the characteristics and expression of cell surface transporters.

Main Methods:

  • Electrophysiology to study receptor properties.
  • Calcium imaging techniques to analyze signal dynamics.
  • Molecular biology methods to assess transporter expression.

Main Results:

  • Detailed characterization of neuronal nicotinic receptor subtypes.
  • Identification of key factors influencing calcium signal modulation.
  • Insights into the role of specific cell surface transporters.

Conclusions:

  • The studies provide novel insights into the complex signaling networks of chromaffin cells.
  • This research deepens the understanding of functional regulation in these cells.

Related Experiment Videos