Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple Sclerosis Impact Scale (MSIS-29): reliability and validity in hospital based samples.

A Riazi1, J C Hobart, D L Lamping

  • 1Neurological Outcome Measures Unit, Institute of Neurology, London, UK.

Journal of Neurology, Neurosurgery, and Psychiatry
|November 20, 2002
PubMed
Summary

The Multiple Sclerosis Impact Scale (MSIS-29) demonstrates reliable and valid psychometric properties across diverse hospital patient samples. These findings support its use as an outcome measure in various clinical settings for multiple sclerosis (MS).

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anti-HBs Immune Complex Levels: A Novel Marker of Hepatitis Flare Following Nucleos(t)ide Analog Withdrawal in HBeAg-negative Chronic Hepatitis B.

The Journal of infectious diseases·2025
Same author

Balancing Efficiency and Accuracy in Hepatitis C Rapid Antibody Testing: Insights From a Cluster Randomised Crossover Trial.

Journal of viral hepatitis·2025
Same author

Editorial: Ultralow HBsAg Levels and the Prediction of Cure in Chronic Hepatitis B.

Alimentary pharmacology & therapeutics·2025
Same author

Polysorbate 80 improves the adhesion and survival of yogurt starters with cholesterol uptake abilities.

Saudi journal of biological sciences·2022
Same author

New insights into the effects of ethylene on ABA catabolism, sweetening and dormancy in stored potato tubers.

Postharvest biology and technology·2021
Same author

Direct Measurement of Single-Molecule Ligand-Receptor Interactions.

The journal of physical chemistry. B·2020

Area of Science:

  • Clinical assessment
  • Psychometrics
  • Multiple Sclerosis (MS) research

Background:

  • Rating scales' psychometric properties are sample-dependent, requiring validation in different populations.
  • The Multiple Sclerosis Impact Scale (MSIS-29) was initially developed using a community-based sample.
  • Key characteristics of the initial MSIS-29 development sample were not fully known.

Purpose of the Study:

  • To evaluate the psychometric properties of the MSIS-29 in three distinct hospital-based samples.
  • To assess MSIS-29 performance in patients undergoing rehabilitation, corticosteroid treatment for relapses, and those with primary progressive MS.

Main Methods:

  • Recruitment of individuals with MS from three clinical settings.
  • Administration of the MSIS-29 and other health measures.

Related Experiment Videos

  • Evaluation of MSIS-29 data for quality, scaling assumptions, acceptability, reliability, and validity, with comparisons to a community-based study.

    • Main Results:

    • Data from 233 participants (rehabilitation, corticosteroids, primary progressive MS) were analyzed.
    • Low missing data (or=0.91) were observed across all samples.
    • MSIS-29 correlations with other scales aligned with hypotheses, and findings were consistent with community samples.

    Conclusions:

    • The MSIS-29 exhibits consistent psychometric properties across three hospital-based patient groups.
    • Its performance in clinical settings mirrors that observed in community samples.
    • These results reinforce the MSIS-29's utility as an outcome measure in diverse clinical contexts for MS.