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Updated: Sep 28, 2026

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Collecting And Measuring Wound Exudate Biochemical Mediators In Surgical Wounds
Published on: October 20, 2012
Scientific analysis of phenol nail surgery
Jeffrey S Boberg1, M Shane Frederiksen, Francois M Harton
1American Board of Podiatric Surgery, USA.
Journal of the American Podiatric Medical Association
|November 20, 2002
Abstract:
Chemical matrixectomy using phenol is one of the most common surgical procedures for the permanent removal of toenails. The concentration of phenol solution and duration of its application have varied widely and have not been subjected to scientific study. The authors studied the histologic effects of phenol on the nail matrix and determined the optimal concentration of phenol and time the phenol solution needs to be in contact with the nail bed.

