The value of premedication in diminishing salivary secretions

A study has been carried out on the anti-sialogogue effect of some drugs used in premedication. Among different anaesthetic agents used in this study halothane appeared to be the least effective in stimulating salivary secretions. Pethidine-atropine combination proved to be very satisfactory as an anti-sialogogue. Atropine came next, where its intravenous route of administration was more satisfactory in short procedures than its intramuscular route.