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Published on: December 11, 2013
Percutaneous interventions for lower-extremity peripheral atherosclerotic disease
1Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, USA.
Insights
Peripheral arterial disease interventions offer alternatives to surgery for claudication and critical limb ischemia. Percutaneous treatments provide feasible options, preserving surgical choices and improving patient outcomes.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Peripheral Arterial Disease Management
Background:
- Peripheral arterial disease (PAD) causes claudication and critical limb ischemia, impacting quality of life.
- Coexisting coronary artery disease increases risks associated with surgical revascularization.
- Percutaneous catheter-based interventions present a viable alternative for PAD treatment.
Purpose of the Study:
- To evaluate the efficacy and role of percutaneous interventions in managing peripheral arterial disease.
- To compare percutaneous revascularization with traditional surgical approaches.
- To assess outcomes for iliac, femoropopliteal, and below-the-knee interventions.
Main Methods:
- Review of percutaneous catheter-based interventions for PAD.
- Analysis of iliac artery balloon angioplasty and stenting outcomes.
- Evaluation of femoropopliteal and below-the-knee percutaneous revascularization results.
Main Results:
- Iliac artery angioplasty demonstrates high initial success and long-term patency; stenting is beneficial for dissections or stenosis.
- Femoropopliteal revascularization shows high restenosis rates; stenting is reserved for specific complications.
- Below-the-knee interventions show promising short-term results for critical limb ischemia in high-risk patients.
Conclusions:
- Percutaneous interventions are effective alternatives and adjuncts to surgery for PAD.
- Iliac interventions, particularly with stenting, offer durable results.
- Careful patient selection and technique are crucial for successful femoropopliteal and below-the-knee revascularization.
Abstract:
Patients with peripheral arterial disease frequently develop symptoms of claudication that interfere with ambulation and adversely affect quality of life, and some develop critical limb ischemia. Many of these patients have coexisting coronary artery disease, and surgical revascularization poses risks of perioperative myocardial infarction and cardiovascular death. Peripheral catheter-based interventions are a feasible alternative. Percutaneous treatment can preserve the surgical option and is often used as an adjunct to surgery by addressing inflow stenoses and limiting the extent of surgical reconstruction that is necessary. Iliac artery balloon angioplasty has been shown to have a high rate of initial procedural success and long-term patency, and the use of stents is promising, especially in cases complicated by flow-limiting dissection or significant residual stenosis. Percutaneous revascularization of the femoropopliteal arteries has shown high restenosis rates and stents should be confined, at present, to flow-limiting dissections or inadequate results from balloon angioplasty alone. The indication for percutaneous revascularization below the knee is typically limited to those patients with critical limb ischemia who are at high risk for surgical reconstruction; short-term results with modern equipment have been promising and can salvage ischemic limbs.
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