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Related Experiment Videos

Novel suture device for beating-heart mitral leaflet approximation.

Ottavio Alfieri1, John A Elefteriades, Robert J Chapolini

  • 1Hospital San Raffaele, Milan, Italy.

The Annals of Thoracic Surgery
|November 21, 2002
PubMed
Summary
This summary is machine-generated.

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A novel suturing device enables safe and effective beating-heart mitral valve repair (Alfieri type) without cardiopulmonary bypass. This technique shows promise for treating mitral regurgitation in heart failure and ischemic conditions.

Area of Science:

  • Cardiovascular Surgery
  • Medical Devices
  • Surgical Innovation

Background:

  • Mitral valve repair traditionally requires cardiopulmonary bypass.
  • Minimally invasive techniques are sought to reduce surgical risks.
  • The Alfieri technique offers a specific approach to mitral valve repair.

Purpose of the Study:

  • To evaluate a novel suturing device for Alfieri-type mitral valve repair.
  • To assess the feasibility of performing this repair on a beating heart without cardiopulmonary bypass.
  • To determine the safety and efficacy of the device in animal models.

Main Methods:

  • Eight healthy adult sheep underwent anesthesia and left thoracotomy.
  • A novel suturing device was used to approximate mitral leaflets on a beating heart.

Related Experiment Videos

  • Echocardiography and pressure monitoring guided suture placement and deployment.
  • Two sutures were placed across the leaflets, tied, and cut using the device.

    • Main Results:

    • The device successfully grasped and approximated mitral leaflets in all subjects.
    • Echocardiography confirmed successful suture deployment and normal valve hemodynamics.
    • Autopsy verified mid-leaflet approximation with no observed tissue damage.

    Conclusions:

    • The novel suturing device allows safe and consistent Alfieri-type mitral valve repair on a beating heart without cardiopulmonary bypass.
    • This technique holds potential for treating ischemic mitral regurgitation and mitral regurgitation in heart failure.
    • The device represents a significant advancement in minimally invasive cardiac surgery.