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Updated: Sep 28, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Atrial septal defect and myocardial infarct
1Section of Cardiothoracic Surgery, Mercy Hospital Wilkes-Barre, Pennsylvania 18702-3545, USA. ncc717@aol.com
Insights
An atrial septal defect can cause acute myocardial infarction by increasing left-to-right shunting, leading to heart muscle damage and right ventricular dysfunction. This case report details such a scenario.
Area of Science:
- Cardiology
- Cardiovascular Research
- Medical Case Reports
Background:
- Acute myocardial infarction (AMI) with normal coronary arteriography necessitates investigating alternative etiologies.
- Atrial septal defects (ASDs) are congenital heart conditions that can present atypically in adults.
- Left-to-right shunting in ASDs can increase the risk of cardiovascular complications.
Observation:
- This case report presents a patient experiencing acute myocardial infarction despite having normal coronary arteries.
- The diagnostic workup revealed the presence of an atrial septal defect.
- Hemodynamic assessment indicated significant left-to-right shunting through the ASD.
Findings:
- The acute increase in left-to-right shunting associated with the atrial septal defect was identified as the likely cause of myocardial necrosis.
- Right ventricular dysfunction was observed, consistent with increased volume load from the shunt.
- The findings highlight a rare but critical presentation of ASD.
Implications:
- Clinicians should consider atrial septal defects in the differential diagnosis of myocardial infarction with unobstructed coronary arteries.
- Early diagnosis and closure of ASDs may prevent severe cardiac events like myocardial infarction.
- This case underscores the importance of comprehensive etiological investigation in cardiology.
Abstract:
The etiology for an acute myocardial infarction with normal coronary arteriography should rule in and rule out the presence of an atrial septal defect. Acute increases in left to right shunting with an atrial septal defect may lead to episodes of myocardial necrosis and right ventricular dysfunction. This case report describes such a scenario.
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