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Accuracy of displayed values of tidal volume in the pediatric intensive care unit
Rosemary A Castle1, Catherine J Dunne, Quen Mok
1Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, UK.
Insights
Ventilator expired tidal volumes (VT(E)) measured at the expiratory valve are inaccurate in children. Measurement at the airway opening is crucial for reliable ventilation monitoring.
Area of Science:
- Pediatric critical care medicine
- Respiratory physiology
- Mechanical ventilation
Background:
- Accurate measurement of expired tidal volumes (VT(E)) is essential for effective mechanical ventilation in children.
- Many ventilators measure exhaled volume at the expiratory valve, but the accuracy of these readings is not always clear.
Purpose of the Study:
- To assess the accuracy of expired tidal volumes (VT(E)) displayed by a frequently used ventilator (Servo 300) that measures exhaled volume at the expiratory valve.
- To compare the ventilator's displayed VT(E) with measurements taken at the airway opening.
Main Methods:
- A prospective study was conducted in a pediatric tertiary referral center.
- 56 intubated children (3 weeks to 16.6 years) on Servo 300 ventilators were included.
- Exhaled VT(E) was measured simultaneously using the Servo 300 and a validated CO2SMO Plus respiratory monitor (airway opening measurement).
Main Results:
- The CO2SMO Plus respiratory monitor demonstrated in vitro accuracy within +/-5%.
- The Servo 300's displayed VT(E) overestimated true VT(E) by 2-91%, with errors varying by pressure, VT(E), and circuit size.
- After correction for circuit compliance, the Servo 300's effective VT(E) underestimated true VT(E) by up to 64% in infants and overestimated by up to 29% in older children.
Conclusions:
- The accuracy of delivered tidal volumes is highly dependent on the measurement site.
- Ventilator-displayed VT(E) measured at the expiratory valve is an inconsistent and misleading indicator of true delivered volumes.
- Measurement at the airway opening is necessary for accurate ventilation monitoring in pediatric patients.
Objectives:
To assess the accuracy of the expired tidal volumes (VT(E)) displayed by one of the most frequently used ventilators that measures exhaled volume at the expiratory valve.
Design:
Prospective study.
Setting:
The intensive care units of a pediatric tertiary referral center in London, UK.
Patients:
A total of 56 intubated children aged between 3 wks and 16.6 yrs who were clinically stable and ventilated with a Servo 300 ventilator.
Interventions:
The CO2SMO Plus respiratory monitor, which measures flow at the airway opening, was validated using calibrated syringes and appropriate tracheal tubes and connections. Simultaneous in vivo recordings of VT(E) from the Servo 300 and CO2SMO Plus were compared before (displayed Servo VT(E)) and after (effective Servo VT(E)) compensating for ventilator circuit compliance.
Measurements And Main Results:
The in vitro accuracy of the CO2SMO Plus was within +/-5% over a wide range of volumes and measurement conditions. The displayed Servo 300 VT(E) overestimated the true VT(E) by between 2% and 91%. The magnitude of error varied within and between children, according to pressure change (peak inspiratory pressure minus positive end-expiratory pressure), VT(E), and circuit size. Mean (sd) error was 32% (20%) in 40 children with displayed Servo VT(E) of <160 mL and 18% (6%) in 16 subjects with displayed Servo VT(E) of >/=160 mL. After correcting for gas compression, effective VT(E) from the Servo 300 underestimated the true VT(E) by up to 64% in the smallest infants but continued to overestimate by as much as 29% in older children.
Conclusions:
The accuracy of tidal volume values is crucially dependent on the site of measurement. Unless measured at the airway opening, displayed values are an inconsistent and misleading indicator of the true volumes delivered.
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