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Breast cancer chemoprevention--an update
1Academic Division of Breast Surgery, St. George's Hospital and Medical School, London, UK. kefahmokbel@hotmail.com
Current Medical Research and Opinion
|November 22, 2002
Abstract:
This article reviews the recent findings of the IBIS-1 and ATAC trials regarding the role of tamoxifen and anastrozole in the chemoprevention of breast cancer. It also emphasises the need to individualise chemoprevention strategies, and to identify high-risk women who are most likely to develop oestrogen receptor (ER)-positive breast cancer. The prevention of ER-negative disease requires further research, and is likely to be challenging.