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Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes
Published on: November 1, 2012
Unique hole-trapping property of the degenerate base,2-amino-7-deazaadenine
Akimitsu Okamoto1, Kazuo Tanaka, Isao Saito
1Department of Synthetic Chemistry and Biological Chemistry, Faculty of Engineering, Kyoto University, Japan.
Bioorganic & Medicinal Chemistry Letters
|November 22, 2002
Abstract:
An artificial degenerate nucleobase, 2-amino-7-deazaadenine (1) showed remarkably high hole-trapping efficiency, similar to that of (Z)G and superior to that of the GGG triplet. The hole-trapping efficiency varied with the counterbase that base-pairs with 1.
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