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Antitrichomonal strains of Bacillus thuringiensis
Shigeo Kondo1, Eiichi Mizuki, Tetsuyuki Akao
1Department of Parasitology, Aichi Medical University School of Medicine, Nagakute, Aichi, 480-1195, Japan. kondo@aichi-med-u.ac.jp
Abstract:
Parasporal inclusion proteins from a total of 816 Bacillus thuringiensis strains isolated in Japan were examined for antitrichomonal activity against Trichomonas vaginalis. Ten strains of B. thuringiensis inhibited the growth of T. vaginalis in 48 h cultures at 37 degrees C. Moreover, the B622 and B626 strains clearly showed trichomonacidal effects against T. vaginalis. The H antigen serotypes of both strains were identified as H13/29 (pakistani/amagiensis). The parasporal inclusion protein from both strains consisted of three major polypeptides of 77, 45 and 25 kDa.