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New saponins from the starfish Certonardoa semiregularis
Weihong Wang1, Famei Li, Naseer Alam
1College of Pharmacy, Pusan National University, Busan 609-735, Korea.
Journal of Natural Products
|November 26, 2002
Abstract:
Ten new saponins designated as certonardosides A-J (1-5, 7-11) and the known halityloside D (6) were isolated from the brine shrimp active fraction of the MeOH extract of the starfish Certonardoa semiregularis. The structures were determined on the basis of spectral analysis and chemical manipulation. The compounds were evaluated for antiviral activity against HIV, HSV, CoxB, EMCV, and VSV and displayed insignificant activity within the range of noncytotoxic concentrations.