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Nanjiols A-C, new steroids from the Chinese soft coral Nephthea bayeri
Zhi-Yu Shao1, Da-Yuan Zhu, Yue-Wei Guo
1State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, People's Republic of China.
Abstract:
Three new polyoxygenated steroids, nanjiol A (1), B (2), and C (3), were isolated from an East China Sea soft coral Nephthea bayeri, and their structures were characterized by spectroscopic methods and comparison with known compounds. The new molecules were structurally related to (20S)-cholesta-1,4-diene-18,20-diol-3-one (4), a typical metabolite from the black coral Antipathes subpinnata.