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Linear accelerator radiosurgery for meningiomas in and around the cavernous sinus
Roberto Spiegelmann1, Ouzi Nissim, Janna Menhel
1Stereotactic Radiosurgery Unit, Department of Neurosurgery, The Chaim Sheba Medical Center, Tel Hashomer, Israel.
Neurosurgery
|November 26, 2002
Summary
Linear accelerator radiosurgery effectively controls cavernous sinus meningiomas in 97.5% of patients. This treatment shows no mortality and minimal side effects, making it a safe option for managing these tumors.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Oncology
Background:
- Cavernous sinus meningiomas are complex tumors requiring effective treatment.
- Linear accelerator radiosurgery offers a precise therapeutic approach.
Purpose of the Study:
- To evaluate the efficacy and safety of linear accelerator radiosurgery for cavernous sinus meningiomas.
- To assess tumor growth control and treatment-related side effects.
Main Methods:
- Retrospective analysis of 42 patients treated between 1993 and 2001.
- Mean radiation dose of 14 Gy delivered to tumor margin.
- Median follow-up of 36 months.
Main Results:
- Tumor growth control achieved in 97.5% of patients.
- No mortality or permanent extraocular motor/pituitary dysfunction observed.
- Low incidence of treatment-related complications, including trigeminal neuropathy (4.7%) and visual field defects (2.8%).
Conclusions:
- Linear accelerator radiosurgery is a highly effective treatment for cavernous sinus meningiomas.
- The procedure demonstrates a high tumor control rate with minimal morbidity.
- This modality represents a safe and effective therapeutic option.