Related Experiment Videos
Giant pilomatrixoma (Malherbe calcifying epithelioma)
Archives of Surgery (Chicago, Ill. : 1960)
|January 1, 1976
Summary
Pilomatrixoma, a rare skin tumor, can mimic common cysts but presents as an invasive lesion. Wide excision and skin grafting offer a satisfactory outcome for this calcifying epithelioma.
Area of Science:
- Dermatology
- Pathology
- Surgical Oncology
Background:
- Pilomatrixoma, also known as Malherbe calcifying epithelioma, is a benign skin appendage tumor.
- It often presents as a subcutaneous nodule, superficially resembling inclusion or sebaceous cysts.
Observation:
- A case of an unusually large, ulcerated, and locally invasive pilomatrixoma in a 56-year-old woman is presented.
- Histopathological examination revealed characteristic features: ghost (shadow) cells, basophilic cells, keratin pearls, and calcifications.
Findings:
- The pilomatrixoma demonstrated typical histopathological markers of the condition.
- The locally invasive nature of the tumor necessitated aggressive surgical management.
Implications:
- Wide surgical excision combined with skin grafting is an effective treatment for locally invasive pilomatrixoma.
- Early diagnosis and appropriate surgical intervention are crucial for favorable patient outcomes in pilomatrixoma cases.