Related Experiment Videos
Issues related to subgroup analysis in clinical trials
Lu Cui1, H M James Hung, Sue Jane Wang
1lu.cui@aventis.com
Abstract:
Interpretation of subgroup findings is a difficult task. The attempt of this article is to clarify confusions on subgroup analysis and to give some practical suggestions on how to avoid mistakes in interpreting subgroup outcome. We believe that the correct interpretation of subgroup findings is closely related to the intrinsic statistical property and validity of the subgroup analysis. A systematic discussion on subgroup analysis from a statistical point of view will be helpful to clinical trial practitioners.
Related Concept Videos
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Clinical Trials
There are four phases in a clinical trial. A phase one...
Clinical Trials: Overview
Comparing the Survival Analysis of Two or More Groups
Hazard Ratio
For example, in a clinical trial evaluating a...
Preclinical Development: Overview