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Lung and thorax development during adolescence: relationship with pubertal status
1Laboratory of Respiratory Physiology, Hĵpital d'Enfants Armand Trousseau, Paris, France.
The European Respiratory Journal
|November 27, 2002
Summary
This study defines reference values for adolescent lung function, considering thoracic volume index and pubertal stage. It reveals distinct lung development patterns in males and females during puberty.
Area of Science:
- Pulmonary Medicine
- Adolescent Physiology
- Respiratory Health
Background:
- Adolescent lung function varies significantly due to differing growth patterns.
- Establishing accurate reference values requires accounting for pubertal development.
- Previous studies may not adequately address these developmental variations.
Purpose of the Study:
- To establish reference values for lung volumes and the lung transfer factor for carbon monoxide (TL,CO) in adolescents.
- To incorporate thoracic volume index (TVI) and pubertal stage (PST) into prediction equations.
- To analyze sex-specific differences in lung development during adolescence.
Main Methods:
- Cross-sectional study involving 51 males and 52 females.
- Measurements included functional residual capacity, vital capacity, total lung capacity, and TL,CO.
- Thoracic volume index (TVI) and pubertal stage by Tanner scale (PST) were assessed.
Main Results:
- In males, lung volumes and TL,CO increased with age, correlating with TVI.
- In females, height was the primary correlate for lung volumes post-menarche.
- Pubertal stage (PST) was the strongest correlate for TL,CO in both sexes, with height also significant in males.
Conclusions:
- Prediction equations for adolescent lung function were developed, incorporating TVI and PST.
- Male lung and thoracic development continue through puberty.
- Female lung development largely concludes after menarche.