Breast Surgery International--breast cancer in developing countries

Area of Science:

• Oncology
• Global Health
• Surgical Sciences

Background:

• Breast Surgery International (BSI) was established to advance breast surgery globally, with a focus on developing countries.
• Locally advanced breast cancer (LABC) presents distinct challenges in resource-limited settings.
• Disparities in diagnosis, management, and treatment exist due to socioeconomic and cultural barriers.

Purpose of the Study:

• To summarize the current situation of locally advanced breast cancer (LABC) in two African countries and Malaysia.
• To highlight the differences in LABC management compared to established international recommendations.
• To emphasize the need for tailored strategies and international collaboration in managing LABC in developing regions.

Main Methods:

• Edited summary of a symposium focused on LABC in developing countries.
• Analysis of diagnostic, management, and treatment disparities.
• Review of clinical characteristics, including younger age at onset and higher male incidence.

Main Results:

• Significant resource limitations, lack of facility access, and socioeconomic barriers impact LABC care.
• Clinical presentation often includes younger patients, a notable proportion of male cases, and predominantly locally advanced disease.
• Standard treatment modalities (chemotherapy, surgery, radiotherapy, hormonal therapy) require adaptation.

Conclusions:

• International collaboration through organizations like BSI is crucial for addressing LABC in developing countries.
• Training opportunities and collaborative research are vital for improving outcomes for the world's most common female malignancy.
• Tailored, rational treatment plans integrating chemotherapy, surgery, radiotherapy, and hormonal therapy are essential for LABC management.