Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Status of lymph node staging.

O E Nieweg1, S H Estourgie, E E Deurloo

  • 1Department of Surgery, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam. o.nieweg@nki.nl

Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society
|November 27, 2002
PubMed
Summary

Sentinel node biopsy offers accurate staging information, potentially sparing 60% of patients unnecessary axillary node dissection. Further research will refine techniques for optimal lymph node metastasis identification.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Survival outcomes for patients with invasive lobular cancer by MammaPrint: Results from the MINDACT phase III trial.

European journal of cancer (Oxford, England : 1990)·2025
Same author

Five-year analysis of neoadjuvant dabrafenib and trametinib for stage III melanoma.

Annals of oncology : official journal of the European Society for Medical Oncology·2024
Same author

Hypofractionated or Conventionally Fractionated Adjuvant Radiotherapy After Regional Lymph Node Dissection for High-Risk Stage III Melanoma.

Clinical oncology (Royal College of Radiologists (Great Britain))·2022
Same author

Omitting SLNB in Breast Cancer: Is a Nomogram the Answer?

Annals of surgical oncology·2021
Same author

Predicting recurrence in patients with sentinel node-negative melanoma: validation of the EORTC nomogram using population-based data.

The British journal of surgery·2021
Same author

Pathological response and tumour bed histopathological features correlate with survival following neoadjuvant immunotherapy in stage III melanoma.

Annals of oncology : official journal of the European Society for Medical Oncology·2021

Area of Science:

  • Oncology
  • Surgical Pathology
  • Medical Diagnostics

Background:

  • Axillary node dissection (AND) is a standard procedure for staging breast cancer.
  • AND is associated with significant patient morbidity.
  • Sentinel node biopsy (SNB) presents a less invasive alternative for staging.

Purpose of the Study:

  • To evaluate the potential of SNB for accurate cancer staging.
  • To determine the optimal SNB technique.
  • To reduce the need for AND in patients without lymph node metastases.

Main Methods:

  • Lymphatic mapping to identify sentinel lymph nodes.
  • Analysis of sentinel lymph node for metastases.
  • Comparison of SNB outcomes with AND.

Related Experiment Videos

Main Results:

  • SNB has the potential for more accurate staging than AND.
  • Approximately 60% of patients may avoid unnecessary AND.
  • Advancements in technology enhance prognostic information from primary tumors and sentinel nodes.

Conclusions:

  • SNB is a promising, less invasive staging method.
  • Further research and long-term studies are needed to establish optimal SNB techniques.
  • SNB can potentially spare a significant number of patients from the morbidity of AND.