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Updated: Sep 28, 2026

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
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Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine

Published on: February 24, 2023

Melanoma vaccines

Miguel-Angel Perales1, Jedd D Wolchok

  • 1Clinical Immunology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center and Joan and Sanford I. Weill Medical College of Cornell University, 1275 York Avenue, New York, NY 10021, USA. peralesm@mskcc.org

Cancer Investigation
|November 27, 2002
PubMed

The identification of antigens on tumor cells has led to significant contributions to the field of immunotherapy. One of the most active areas under investigation in cancer immunotherapy is the development of vaccines against melanoma antigens. Induction of immunity against tumor antigens can follow multiple routes using different mechanisms. Crucial to the development of active immunization and other immunotherapies is the discovery and understanding of the molecular identity of antigens and the mechanisms involved in tumor immunity, as well as escape from immunity. In this review, we will discuss strategies to induce active immunity against melanoma.

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