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Myofibroblastoma in the suprasellar region. Case report
Naoki Shinojima1, Kazutaka Ohta, Shigetoshi Yano
1Department of Neurosurgery, Kumamoto University School of Medicine, Kumamoto, Japan. 008m9020@med.stud.kumamoto-u.ac.jp
Journal of Neurosurgery
|November 27, 2002
Summary
This report details a rare intracranial myofibroblastoma in a woman
Area of Science:
- Neurosurgery
- Oncology
- Pathology
Background:
- Myofibroblastomas are rare benign mesenchymal tumors.
- Intracranial myofibroblastomas are exceptionally rare, with only two prior reported cases.
- This study presents a third case of intracranial myofibroblastoma.
Observation:
- A 34-year-old woman presented with sudden headache and progressive visual disturbance.
- Imaging revealed a mixed-density mass in the suprasellar region.
- The tumor exhibited heterogeneous enhancement on MRI.
Findings:
- Subtotal tumor removal was achieved via a right frontobasal translamina-terminalis approach.
- Histology showed alternating spindle and round cells with collagen fibers.
- Immunohistochemistry confirmed intense alpha-smooth-muscle actin reactivity, identifying myofibroblasts.
Implications:
- The patient experienced immediate visual improvement post-surgery.
- The tumor is presumed to have a meningeal origin in the suprasellar region.
- This case expands the understanding of rare intracranial tumors and their surgical management.