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Updated: Jan 28, 2026

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Published on: February 10, 2023
A spontaneous uterine sarcoma in a rhesus monkey (Macaca mulatta)
R Plesker1, C Coulibaly, U Hetzel
1Paul-Ehrlich-lnstitut, Langen, Germany.
A rare uterine sarcoma metastasized in a rhesus monkey. This case highlights the importance of recognizing uterine tumors in non-human primates, aiding in early diagnosis and treatment strategies.
Area of Science:
- Veterinary Pathology
- Primate Oncology
- Comparative Oncology
Background:
- Malignant mesenchymal uterine tumors are infrequently reported in primates.
- Understanding uterine sarcoma in non-human primates is crucial for comparative oncology.
Observation:
- A 17-year-old rhesus monkey presented with symptoms including abdominal pain, nausea, anemia, and bloody vaginal discharge.
- Diagnostic laparoscopy revealed pelvic adhesions and ascites.
- Necropsy identified a large uterine tumor with metastases to the omentum.
Findings:
- Histological examination confirmed a sarcoma in both the uterus and metastases.
- The sarcoma exhibited scant connective tissue and well-differentiated cell nuclei.
Implications:
- This case expands the understanding of uterine sarcoma in rhesus monkeys.
- It underscores the need for vigilance in diagnosing uterine neoplasms in primates.
- Further research into primate uterine tumors can inform human cancer studies.
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