Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypolipemic agents for stroke prevention.

Didier Leys1, Dominique Deplanque, Christian Lucas

  • 1dleys@chru-lille.fr

Clinical and Experimental Hypertension (New York, N.Y. : 1993)
|November 27, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Paired CycleGAN-based virtual staining for 3D X-ray histology of bone-implant systems.

Journal of synchrotron radiation·2026
Same author

Immunological efficacy and safety of influenza vaccination in adults with sarcoidosis: the SARCOVAC study.

Vaccine·2026
Same author

Combination of Clopidogrel With PPIs or P-CABs: Beware of Risky Interactions.

Stroke·2026
Same author

Comparison of the effect of donepezil and a combination of donepezil and mefloquine (THN201) on cognition during a scopolamine challenge in healthy participants.

Experimental and clinical psychopharmacology·2026
Same author

Predictive factors of effectiveness of occipital nerve stimulation for chronic cluster headache: data from for the French ONS registry.

The journal of headache and pain·2026
Same author

Being 80 years old in a rapidly changing world….

Therapie·2026
Same journal

Adiponectin improves the aortic dissection by inhibiting inflammatory cell infiltration and macrophage pyroptosis.

Clinical and experimental hypertension (New York, N.Y. : 1993)·2026
Same journal

Electroacupuncture for essential hypertension: Mechanistic insights, current clinical evidence, and translational challenges.

Clinical and experimental hypertension (New York, N.Y. : 1993)·2026
Same journal

Association of intracranial atherosclerotic stenosis with 1-year cognitive impairment after acute ischemic stroke or transient ischemic attack: a nationwide prospective cohort study.

Clinical and experimental hypertension (New York, N.Y. : 1993)·2026
Same journal

Frailty as a mediator of the association between hyperuricemia and stroke risk: A prospective cohort study.

Clinical and experimental hypertension (New York, N.Y. : 1993)·2026
Same journal

Synergistic impact of nondipper heart rate and blood pressure on left ventricular hypertrophy in essential hypertension.

Clinical and experimental hypertension (New York, N.Y. : 1993)·2026
Same journal

From clinic to home monitoring: Diagnostic strategies and evidence landscape of white-coat uncontrolled hypertension.

Clinical and experimental hypertension (New York, N.Y. : 1993)·2026
See all related articles

Lowering cholesterol with hypolipidemic agents is crucial for stroke prevention. Studies show these agents reduce stroke incidence, particularly in high-risk patients, by addressing hypercholesterolemia.

Area of Science:

  • Cardiovascular Medicine
  • Neurology
  • Pharmacology

Background:

  • Hypercholesterolemia is a significant risk factor for stroke.
  • Effective stroke prevention strategies require identifying and treating lipid disorders.

Purpose of the Study:

  • To evaluate the role of hypolipidemic agents in stroke prevention.
  • To consolidate evidence supporting lipid-lowering therapies for reducing stroke incidence.

Main Methods:

  • Review of randomized trials in coronary heart disease patients.
  • Analysis of pooled data from primary and secondary stroke prevention trials.
  • Examination of animal models for neuroprotective effects of hypolipidemic agents.

Main Results:

Related Experiment Videos

  • Established statistical link between abnormal lipid levels (high LDL-c, low HDL-c) and ischemic stroke.
  • Demonstrated reduction in vascular risk and plaque progression with lipid-lowering therapies.
  • Pooled analyses confirm cholesterol reduction decreases stroke incidence, especially in high-risk individuals.

    • Conclusions:

    • Hypolipidemic agents show promise for stroke prevention.
    • Further confirmation in stroke patients is warranted based on existing cardiovascular and asymptomatic individual trial data.
    • Lipid management is a key component of comprehensive stroke prevention.