Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Functional neuroimaging in acute stroke.

Novella Bonaffini1, Marta Altieri, Andrea Rocco

  • 1Chair of Neurology, University of Rome La Sapienza, Viale dell'Università 30, 00185 Rome, Italy.

Clinical and Experimental Hypertension (New York, N.Y. : 1993)
|November 27, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

SafeTy and effectiveness of Atogepant accoRding to the IHS outcome categories: A multicentric, prospective observational study in real life (the 24-week STAR study).

Cephalalgia : an international journal of headache·2026
Same author

Down-sloping high-frequency audiometric findings in ENT-MS-12 auditory screen-positive patients with relapsing-remitting multiple sclerosis: A pilot case series.

Multiple sclerosis and related disorders·2026
Same author

White matter microstructural alterations in episodic cluster headache outside attacks: a tract-based spatial statistics study.

The journal of headache and pain·2026
Same author

Logarithmic subdiffusion from a damped bath model.

Physical review. E·2026
Same author

Translation and validation of the Migraine Interictal Burden Scale (MIBS-4) in an Italian clinical cohort.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same author

Teleneurology vs On-Site Neurology Consultation for Postadmission Hospital Care of Stroke.

JAMA neurology·2026
Same journal

Adiponectin improves the aortic dissection by inhibiting inflammatory cell infiltration and macrophage pyroptosis.

Clinical and experimental hypertension (New York, N.Y. : 1993)·2026
Same journal

Electroacupuncture for essential hypertension: Mechanistic insights, current clinical evidence, and translational challenges.

Clinical and experimental hypertension (New York, N.Y. : 1993)·2026
Same journal

Association of intracranial atherosclerotic stenosis with 1-year cognitive impairment after acute ischemic stroke or transient ischemic attack: a nationwide prospective cohort study.

Clinical and experimental hypertension (New York, N.Y. : 1993)·2026
Same journal

Frailty as a mediator of the association between hyperuricemia and stroke risk: A prospective cohort study.

Clinical and experimental hypertension (New York, N.Y. : 1993)·2026
Same journal

Synergistic impact of nondipper heart rate and blood pressure on left ventricular hypertrophy in essential hypertension.

Clinical and experimental hypertension (New York, N.Y. : 1993)·2026
Same journal

From clinic to home monitoring: Diagnostic strategies and evidence landscape of white-coat uncontrolled hypertension.

Clinical and experimental hypertension (New York, N.Y. : 1993)·2026
See all related articles

Computed tomography (CT) excels at detecting brain bleeds but struggles with early ischemic stroke detection. Functional neuroimaging is crucial for identifying salvageable brain tissue and guiding timely thrombolytic therapy.

Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Background:

  • Computed tomography (CT) is the primary diagnostic tool for acute stroke, highly sensitive for hemorrhage but limited in early ischemic injury detection.
  • Thrombolytic therapy efficacy in acute stroke necessitates advanced imaging to differentiate salvageable tissue from infarct core.
  • Identifying the ischemic penumbra is critical for selecting appropriate patients for time-sensitive thrombolytic treatment.

Purpose of the Study:

  • To review the role of functional neuroimaging in acute stroke assessment.
  • To compare various functional neuroimaging techniques for evaluating acute ischemic stroke.
  • To highlight the importance of advanced imaging in guiding therapeutic decisions for acute stroke.

Main Methods:

  • Discussion of various functional neuroimaging modalities including PET, SPECT, Xenon CT, CTP, DW-MRI, and PW-MRI.

Related Experiment Videos

  • Comparison of the advantages and limitations of each imaging technique in the acute stroke setting.
  • Focus on the clinical utility and accessibility of functional MRI in acute stroke diagnosis.

    • Main Results:

    • CT demonstrates high sensitivity for intracerebral hemorrhage but poor sensitivity for early ischemic changes.
    • Functional neuroimaging techniques offer improved detection of ischemic injury and assessment of tissue viability.
    • Functional MRI is currently the most widespread advanced imaging technique due to its accessibility and comprehensive information.

    Conclusions:

    • Functional neuroimaging plays a pivotal role in acute stroke management by enabling precise patient selection for thrombolytic therapy.
    • While CT is standard for hemorrhage, advanced MRI techniques are essential for characterizing ischemic stroke and guiding treatment.
    • The continuous development of neuroimaging technologies promises further improvements in acute stroke diagnosis and patient outcomes.