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Related Experiment Videos

Gingival enlargement in acromegaly.

I Capoglu1, A B Yilmaz, N Unüvar

  • 1Atatürk University Medical Faculty, Department of Endocrinology, Erzurum, Turkey.

Endocrine
|November 27, 2002
PubMed
Summary

Acromegaly, a condition causing organ overgrowth, can lead to gingival enlargement. This study found that eight out of eleven patients with acromegaly exhibited this oral manifestation, often associated with prognathism.

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Area of Science:

  • Endocrinology
  • Periodontology
  • Oral Medicine

Background:

  • Acromegaly is a hormonal disorder characterized by excessive growth hormone production, leading to overgrowth of various body tissues.
  • Gingival enlargement is a common oral finding, but its association with acromegaly requires further investigation.

Purpose of the Study:

  • To investigate the prevalence and characteristics of gingival enlargement in patients diagnosed with acromegaly.
  • To determine if gingival enlargement is a significant oral manifestation of acromegaly.

Main Methods:

  • Oral examinations were conducted by a periodontist on eleven patients with confirmed acromegaly.
  • Evaluated parameters included plaque index, gingival index, probing pocket depths, and gingival enlargement.
  • Patient history, including disease duration and pituitary adenoma type, was recorded.

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Main Results:

  • Gingival enlargement was observed in eight out of eleven patients (73%).
  • Seven of these patients also presented with prognathism.
  • The duration of acromegaly ranged from 0.2 to 13 years.

Conclusions:

  • Gingival enlargement is a notable oral manifestation in patients with acromegaly.
  • Acromegaly should be considered in the differential diagnosis of unexplained gingival enlargement, especially when accompanied by prognathism.