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Published on: June 2, 2014
Familial cluster headache: a series of 186 index patients
Mohammed El Amrani1, Anne Ducros, Pauline Boulan
1Service de Neurologie, Clinique de Courlancy, Reims, France. mohammed.el-amrani@lrb.ap-hop-paris.fr
Objective:
To investigate the familial occurrence of cluster headache in a series of French patients fulfilling the International Headache Society diagnosis criteria.
Methods:
One hundred eighty-six index patients and 624 first-degree relatives were surveyed.
Results:
A positive family history of cluster headache was found in 20 index patients (10.75%) with 22 affected first-degree relatives (3.4%). In multiplex families 6 of the 68 second-degree relatives that were contacted had cluster headache.
Conclusion:
No precise mode of inheritance could be drawn from the observed repartition of cases within multiplex families.
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