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Rationale and methods for the National Tuberculosis Genotyping and Surveillance Network
Kenneth G Castro1, Harold W Jaffe
1Division of Tuberculosis Elimination, National Center for HIV, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. kcastro@cdc.gov
Emerging Infectious Diseases
|November 28, 2002
Abstract:
Our understanding of tuberculosis (TB) transmission dynamics has been refined by genotyping of Mycobacterium tuberculosis strains. The National Tuberculosis Genotyping and Surveillance Network was designed and implemented to systematically evaluate the role of genotyping technology in improving TB prevention and control activities. Genotyping proved a useful adjunct to investigations of outbreaks, unusual clusters, and laboratory cross-contamination.